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Ophthalamin – bioregulator of the organ of vision


Ophthalamin is produced from the cattle and pig ophthalmic tissues. It is a nucleoprotein complex, which acts selectively on ophthalmic tissue cells promoting the recovery of visual function.

Clinical trials were conducted on 194 patients with retinal dystrophy of various etiology and posttraumatic endothelial epithelial dystrophy of the retina. Control groups consisted of 135 similar patients who underwent standard treatment.

Ophthalamin effectiveness was estimated subjectively and with respect to objective indices. All patients were examined prior to and after treatment according to complex clinical programme , including alongside indispensable standard methods, precise diagnosis of visual functions disturbances, rate of blood flow, the state of external and internal layers of the retina, the state of pigmentary epithelium of the retina.

Standard method of examination included: visual acuity and fields of vision tests, darkness adaptation analysis, intracranial pressure measurement, biomicroscopy of anterior section of the eye and deep optic media, biomicroophthalmoscopy, stereoophthalmoscopy, direct ophthalmoscopy.

Methods of examination included: visocontrastometry, static and multiple perimetry, color perception study, fluorescent angiography of the fundus of the eye, dopplerography and electrophysiological examination.

There were conducted clinical blood and urine tests, blood biochemistry.

Estimation of clinical and laboratory functional parameters showed alterations in all departments of the eye (iris, lens, vitreous body, optic nerve) in patients with retinal dystrophies, which suggested generalization of pathological process with the tendency of progressing with the development of the disease.

As a result of clinical trials, it was established that ophthalamin application gave maximum therapeutic effect in patients with initial forms of retinal degeneration. It was obvious due to vision acuity increase and visual fields expansion (widening of peripheral borders, reduction or disappearance of paracentral scotomas).

Ophthalamin application for patients with posttraumatic visual disturbances promoted 1.3 - 1.4-fold the recovery of epithelial layer completeness and visual acuity.

Incomplicated course of residual period brought to complete recovery and disappearance of signs of blepharospasm, photophobia and final formation of the corneal cicatrix.

Ophthalamin treatment of patients with partial destruction of the cornea in postoperative period helped to escape infectious complications and facilitated corneal transplantation.

Chemical structure and nutritional value of Ophthalamin:

Nutritional substances, %

Vitamins, mg/10 mg

Protein

56,7

Thiamin(B1)

0,09

Fats

9,8

Riboflavin(B2)

0,012

Carbohydrates

<0,01

Niacin(PP)

0

Ashes

2,2

Retinol(A)

0,17

 

à-Tocopherol(E)

0,42

Mineral substances, mg/10mg

Aminoacids, nmol/mg

Aluminium

0,1572

Asparagine

508

Cobalt

0

Threonine

178

Copper

0,0989

Serine

338

Iron

4,26

Glutamine

658

Magnesium

1,66

Proline

365

Calcium

29,15

Glycine

390

Potassium

37,83

Alanine

293

Sodium

422,31

Valine

300

Manganese

0,0244

Methionine

0

Molybdenum

0

Isoleucine

203

Phosphorus

58,45

Leucine

385

Sulfur

126,2

Tyrosine

168

Zinc

12,5

Phenylalanine

203

Lead

0

Histidine

185

Cadmium

0

Lysine

273

 

Arginine

290

Ophthalamin is recommended for accelerated recovery of ophthalmic tissue functions in case of various lesions of the latter, including retinal degeneration and posttraumatic corneal dystrophy. It is also recommended to the elderly for maintaining visual functions.

No side effects have been registered.

It should be stored in a dry cool light protected place.

Dr. Giorgio Castello

Via A. Cecchi, 19/9

16129 – Genova (Italy)

Phone: +39.010.58.94.95

Mobil phone : +39.335.628.34.24

e-mail: castello@tiopoietine.info

 

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