Experience of using Glutoxim in
oncological patients.
S.V.Odintsov, A.P.Nikolaev, N.N.Vinogradova.
Central Clinical Hospital, Medical center at the RF Presidential
Administration, Moscow.
Purpose: To evaluate the
ability of Glutoxim to induce anti-tumor immunity in the interests of improving
the quality of life and anti-tumor therapy tolerance in oncological patients.
Methods:
126 patients were treated, including 49 patients with lung cancer,
30 patients with breast cancer, 14 patients with skin melanoma, 12
patients with colorectal cancer, 6 patients with ovarian carcinoma,
4 patients with gastric carcinoma and 4 patients with liver
carcinoma. Other cases included kidney carcinoma, cervical carcinoma, primary multiple
carcinoma and one case of cancer with unclear primary localization. The first
group (44 patients) received Glutoxim concomitantly with 2nd or
3rd echelon therapy for ovarian carcinoma, breast cancer or lung
cancer. The second group (32 patients) of patients with incurable forms of
cancer (melanoma, lung cancer, liver carcinoma, gastric carcinoma) received
Glutoxim as symptomatic therapy. In the third group (50 patients) Glutoxim
was administered with the aim of prolonging chemotherapy courses in patients
with drastically lowered blood parameters (breast cancer, colorectal cancer,
primary multiple carcinoma).
Results: Good clinical
effect was observed. Chemotherapy tolerance improved, clinical and biochemical
blood parameters restored rapidly. Concomitant Glutoxim therapy was associated
with clinically obvious signs of improved chemotherapy tolerance. Glutoxim
monotherapy improved general clinical condition of the patients, prevented
cytopenia and secondary immune deficiency, and accelerated rehabilitation after
each treatment stage. No side effects or adverse reactions were registered.
Conclusions: Glutoxim is
effective as chemotherapy-accompanying drug in oncological patients and
possesses a marked symptomatic effect in incurable patients.
For more references:
Dr. Giorgio Castello
Corso Torino, 32/6
16129 – Genova (Italy)
Tel: +39.010.58.94.95
Mobil
phone: +39.335.628.34.24
e-mail:
castello@tiopoietine.info